Effect of propolis on diabetes mellitus
Phase 2
- Conditions
- type 2 diabetes.Non-insulin-dependent diabetes mellitus
- Registration Number
- IRCT2014080218659N1
- Lead Sponsor
- Vice Chancellor for Research, Yazd Shahid Sadoughi University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 67
Inclusion Criteria
patients with type 2 diabetes mellitus, diagnosed 5-10 years ago, under treatment with oral hypoglycemic agents.
Exclusion criteria: pregnancy, lactation, insulin therapy, any other diseases such as autoimmune, intestinal, liver, thyroid and cardiovascular diseases, vitamin and mineral supplementation, history of dermal or digestive hypersensitivity to propolis, any severe respiratory disease (such as asthma, chronic bronchitis), report of side effects of propolis tablets.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Fasting Blood Glucose. Timepoint: Before and after intervention. Method of measurement: Enzymatic method (mg/dl).;Fasting insulin. Timepoint: Before and after intervention. Method of measurement: ELISA(mU/l).;Triglyceride. Timepoint: Before and after intervention. Method of measurement: Enzymatic method (mg/dl).;Total cholesterol. Timepoint: Before and after intervention. Method of measurement: Enzymatic method (mg/dl).;LDL-C. Timepoint: before and after intervention. Method of measurement: Friedewald formula (mg/dl).;HDL-C. Timepoint: before and after intervention. Method of measurement: Precipitation(mg/dl).;Insulin resistance, sensitivity. Timepoint: Before and after intervention. Method of measurement: Software.
- Secondary Outcome Measures
Name Time Method HA1C. Timepoint: The baseline and three months after the intervention. Method of measurement: Turbidometry.