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Clinical Trials/NCT02293239
NCT02293239
Completed
N/A

Effects of Whole-Body Electromyostimulation (WB-EMS) Combined With Individualized Nutritional Support on Patients With Malignant Disease Undergoing Curative or Palliative Anti-cancer Treatment

University of Erlangen-Nürnberg Medical School1 site in 1 country278 target enrollmentAugust 2013

Overview

Phase
N/A
Intervention
Not specified
Conditions
Cancer
Sponsor
University of Erlangen-Nürnberg Medical School
Enrollment
278
Locations
1
Primary Endpoint
Physical function - Gait pattern
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

This study evaluates the effects of a 12-week whole-body electromyostimulation (WB-EMS) training combined with individualized nutritional support on body composition, muscle strength and function and quality of life of patients with malignant disease undergoing curative or palliative anti-cancer treatment

Registry
clinicaltrials.gov
Start Date
August 2013
End Date
August 2018
Last Updated
7 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
University of Erlangen-Nürnberg Medical School
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • malignant disease (solid or hematological cancer): head and neck cancer, colorectal carcinoma, small intestinal cancer, gastric cancer, oesophageal cancer, pancreas carcinoma, liver cell carcinoma, cholangiocarcinoma,lung cancer, breast cancer, cervix cancer, ovarian cancer, prostate cancer, renal cell carcinoma, malignant melanoma, patients with leukaemia and malignant lymphomas or Graft-versus-Host-Disease after bone marrow transplantation
  • ongoing or planned curative or palliative anti-cancer therapy

Exclusion Criteria

  • simultaneous participation in other nutritional or exercise intervention trials
  • acute cardiovascular events
  • use of anabolic medications
  • severe neurological diseases
  • skin lesions in the area of electrodes
  • energy active metals in body
  • pregnancy
  • acute vein thrombosis

Outcomes

Primary Outcomes

Physical function - Gait pattern

Time Frame: 12 weeks

Sensor-based gait analysis

Skeletal muscle mass

Time Frame: 12 weeks

Skeletal muscle mass assessed by bioelectrical impedance analysis (in kg)

Secondary Outcomes

  • Patient-reported performance status(12 weeks)
  • Patient-reported Fatigue(12 weeks)
  • Patient-reported Quality of Life (QoL)(12 weeks)
  • Physical function - Endurance(12 weeks)
  • Physical function - Isometric muscle strength(12 weeks)
  • Physical function - Lower limb strength(12 weeks)
  • Inflammatory blood markers(12 weeks)

Study Sites (1)

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