Incidental Finding of Gastrointestinal Stromal Tumors (GISTs) During Laparoscopic Sleeve Gastrectomy, How to Deal? How Much Safety Margin
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Excision Margin
- Sponsor
- Bassem Mohamed Sieda
- Enrollment
- 338
- Locations
- 1
- Primary Endpoint
- Excision of GIST during LSG
- Last Updated
- 6 years ago
Overview
Brief Summary
LSG is thought to be the best choice for obese patients with conincidental GISTs, as a tumour can be resected along with resecting the stomach within the same procedure. The primary endpoint is that, how much does GIST suppose to be far from a staple line to do safe laparoscopic sleeve gastrectomy
Detailed Description
The incidence of unsuspected GIST in LSG specimens in our series was high in comparison to cases reported in the literature. GISTs could be safely removed laparoscopically during LSG surgery with negative microscopic resection margins, with 1-2cm safety margin. Margins less than 1cm, high mitotic rate are adverse prognostic factors. Examining the whole stomach before resection is mandatory and can easily be done during LSG, GIST can be removed safely with LSG
Investigators
Bassem Mohamed Sieda
Assistant professor of general surgery, faculty of medicine
Zagazig University
Eligibility Criteria
Inclusion Criteria
- •All morbid obese patients with BMI more than 35
Exclusion Criteria
- •previous gastric surgery
- •patients with hiatus hernia
- •age under 21 years
Outcomes
Primary Outcomes
Excision of GIST during LSG
Time Frame: 4 years from start of study
we analyzed the incidence of GISTs in patients underwent LSG and investigated whether simultaneous resection can be oncologically adequate. as long as GIST is distal to staple line with a negative margin, laparoscopic sleeve gastrectomy can be done safely.