Incidental Finding of Gastrointestinal Stromal Tumors (GISTs) During Laparoscopic Sleeve Gastrectomy, How to Deal? How Much Safety Margin
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 338
- 试验地点
- 2
- 主要终点
- Excision of GIST during LSG
研究概览
简要总结
LSG is thought to be the best choice for obese patients with conincidental GISTs, as a tumour can be resected along with resecting the stomach within the same procedure. The primary endpoint is that, how much does GIST suppose to be far from a staple line to do safe laparoscopic sleeve gastrectomy
详细描述
The incidence of unsuspected GIST in LSG specimens in our series was high in comparison to cases reported in the literature.
GISTs could be safely removed laparoscopically during LSG surgery with negative microscopic resection margins, with 1-2cm safety margin. Margins less than 1cm, high mitotic rate are adverse prognostic factors.
Examining the whole stomach before resection is mandatory and can easily be done during LSG, GIST can be removed safely with LSG
研究设计
- 研究类型
- Interventional
- 干预模型
- Sequential
- 主要目的
- Treatment
- 盲法
- None
盲法说明
With institutional review board approval from Zagazig University Hospitals 338. A double-centre prospective study was conducted on prospectively collected data of all morbidly. 17 patients in Zagazig University Hospitals, Faculty of Medicine, Egypt and 321 patients done in bariatric surgery excellence unit in a tertiary hospital in Riyadh-KSA.
入排标准
- 年龄范围
- 21 Years 至 42 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All morbid obese patients with BMI more than 35
排除标准
- •previous gastric surgery
- •patients with hiatus hernia
- •age under 21 years
结局指标
主要结局
Excision of GIST during LSG
时间窗: 4 years from start of study
we analyzed the incidence of GISTs in patients underwent LSG and investigated whether simultaneous resection can be oncologically adequate. as long as GIST is distal to staple line with a negative margin, laparoscopic sleeve gastrectomy can be done safely.
次要结局
未报告次要终点
研究者
Bassem Mohamed Sieda
Assistant professor of general surgery, faculty of medicine
Zagazig University