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Selection of Breast Cancer Patients with Low-risk Tumors using MR Imaging

Completed
Conditions
10006291
10006232
breast cancer
Registration Number
NL-OMON36966
Lead Sponsor
niversitair Medisch Centrum Utrecht
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
60
Inclusion Criteria

- 18 years or older
- Female patients
- Eligible for breast-conserving therapy

Exclusion Criteria

- Any prior surgery or radiotherapy to the ipsilateral breast
- Patients planned for neoadjuvant chemotherapy
- Karnofsky score <= 70
- Pregnant or lactating women
- Contra-indications to MRI scanning
Contra-indications to injection of gadolinium based contrast agent

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>The association between preoperative imaging characteristics and post-operative<br /><br>prognostic markers in resection specimens. </p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Comparison of pre-treatment dynamic contrast-enhanced MRI, MR<br /><br>diffusion-weighted imaging, and magnetic resonance spectroscopy (MRS) at 7T to<br /><br>identify low-risk breast cancers.</p><br>
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