Efficacy and safety of hybrid therapy combined with branched-chain amino acid and resistance training in frail patients with cardiovascular disease
Not Applicable
- Conditions
- frail patients with cardiovascular disease
- Registration Number
- JPRN-UMIN000034714
- Lead Sponsor
- Sakakibara Heart Institute
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
Not provided
Exclusion Criteria
Dysphagia, Severe mobility limitations due to stroke or orthopedic disease, Uncontrolled cardiovascular disease, Diagnosis or treatment of cancer,Cognitive impairment; MOCA-J is above 26points, hemodialysis therapy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in skeletal muscle mass after 12-week intervention
- Secondary Outcome Measures
Name Time Method Muscle strength: handgrip strength and isomertic leg strength Short physical performance battery (SPPB) Sarcopenia: AWGS criteria Frailty: J-CHS, Essential frail toolkit eGFR: serum creatinin, cystatin C