To evaluate effect of munditika churna and Haritaki churna in the management of Vatarakta (gout)

Phase 3

Recruiting

• Conditions: Chronic gout, unspecified. Ayurveda Condition: VATARAKTAM,

• Registration Number: CTRI/2023/09/057542
• Lead Sponsor: Pathan Md Junaid Naim Khan

Brief Summary

Vatrakta is one of the Vatavyadhis, a disease where both Vata and Rakta are afflicted by distinct etiological factors. There are 02 types of Vatarakta i.e., Uttana Vatarakta produces symptoms like itching, burning sensation, pain, brown-blackish discolouration of skin. While, Gambhira Vatarakta produces symptoms like swelling, hardness, tenderness, burning sensation, pain. Sometimes numbness is also present. Vatarakta can be corelated with Gout. Gout is the most common inflammatory arthritis in men and in older women. Gout is the most common form of inflammatory arthritis. As the level of uric acid [in men (≤ 7 mg/dl) and women (≤ 6 mg/dl)] crosses its saturation thresholds in physiological fluids urate crystals precipitation starts in the joints leading to gout. In Ayurveda Vatarakta has been described in detail with different useful treatment modalities. One of such treatment for Vatarakta is classicaly recommended in Bhaishajya ratnavali is Munditika churna & Haritaki churna. so, this RCT is planned to evaluate efficacy of both these churna (Munditika & Haritaki churna). The main outcome of this trial is to evaluate improvement in symptoms viz. 1. Shotha (Swelling)2. Kathinya (Stiffness & Hardness)3. Vedanadhikya (Severe pain)4. Daha (Burning sensation)5. Toda (Pricking pain)6. Shyavata & tamrata (Blackish or Coppery joint discolouration)7. Sphurana (Twitching sensation) and changes in changes in sr. Uric acid levels.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-09-25
• Last Update Posted: 2024-04-25

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: Not specified
• Target Recruitment: 160

Inclusion Criteria

• 1. Participants having classical sign & symptoms of Vatarakta like.
• 1. Shotha (Swelling) 2. Kathinya (Stiffness & Hardness) 3. Vedanadhikya (Severe pain) 4. Daha (Burning sensation) 5. Toda (Pricking pain) 6. Shyavata & tamrata (Blackish or Coppery) 7. Sphurana (Twitching sensation) 8. Participants having age group between 18 years to 60 years 9. Participants having Serum Uric acid level > 7 mg/dl in Males & >6 mg/dl in Females 10. Participants will be selected irrespective Gender, Religion, Socio-Economic status.

Exclusion Criteria

• Participants having complications like Paka, Khanja, Pangulya and Sandhi vakrata will be excluded.
• Alcohol and drug abusers, Pregnant and lactating women 3.
• Symptomatic participants with clinical evidence of Kidney failure 4.
• k/c/o Malignancy, poorly controlled DM, HTN 5.
• Participants having other acute or complicated systemic disease which require long term drug treatment.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improvement in vatarakta sign & symptoms	15th, 30th, 45th day

Secondary Outcome Measures

Name	Time	Method
decrease in Hyperuricemia (Sr. Uric acid) level	45th day

Trial Locations

Locations (1)

Sanjivan hospital & research centre; 🇮🇳 Ahmadnagar, MAHARASHTRA, India

Sanjivan hospital & research centre

🇮🇳Ahmadnagar, MAHARASHTRA, India

Pathan Md Junaid Naim Khan

Principal investigator

7709483864

junaidklm86@gmail.com