europsychiatric long term symptoms following COVID-19: Causes, functional correlates and pathomechanisms
Recruiting
- Conditions
- 09.9! Post-COVID syndrome
- Registration Number
- DRKS00027230
- Lead Sponsor
- Zentralinstitut für Seelische Gesundheit, Medizinische Fakultät Mannheim / Universität Heidelberg, Klinik für Psychiatrie und Psychotherapie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
Post-COVID syndrome (WHO definition) including neuropsychiatric symptoms; age 18-65 years
Exclusion Criteria
Pre-existing cognitive deficits, pre-existing sleep disorder, for MRI investigation: contraindication against magnetic resonance tomography
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Magnetic resonance spectroscopy signs of disturbed neuronal energy metabolism
- Secondary Outcome Measures
Name Time Method 1.) Disturbed sleep architecture in patients with long-COVID compared to subjects with and without previous COVID-19-disease <br>2.) Clinical symptoms correlate with signs of disturbed neuronal energy metabolism in patients with long-COVID<br>3.) Genetic differences between subjects with previous COVID-19 with and without long-COVID are indicative of factors predisposing to long-COVID<br>4.) Exploratively: Differences in microbiome between healthy subjects without previous COVID-19 and subjects after COVID-19 with and without long-COVID