eurological manifestations of Long Covid-19 in Germany - an observational study (NEURO LC-19 DE)
- Conditions
- 09.9! Post-Covid 19 condition: intended for cases in which the association of a current condition classified elsewhere with a previous coronavirus disease should be coded.U09.9!
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 700
Inclusion Criteria
PCS according to NICE guidelines.
- Confirmation of initial acute infection by positive SARS-CoV-2-
PCR result or serological detection of SARS-CoV-2 nucleocapsid
nucleocapsid antibodies
- Leading cognitive deficits in the context of PCS
Exclusion Criteria
- Acute COVID-19 disease (<4 weeks).
- Absence of confirmation of acute infection by PCR or specific
serology
- Present symptoms more likely to be explained by other
other diagnosis
- Pregnancy
- Breastfeeding
- Insufficient knowledge of German
- Participation in an AMG study
- beinig under care
- not being able to give consent
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - Structured recording of previous illnesses, medication,<br>course of the disease, symptoms and therapy of the patients<br>- Structured recording of self-report questionnaires on symptoms<br>- Clinical-neurological examination<br>- Neuropsychological testing
- Secondary Outcome Measures
Name Time Method - In addition, co-recording and analysis of imaging, neurological diagnostics (e.g. EEG and electrophysiology) and biomaterial electrophysiology) and biomaterial (blood and cerebrospinal fluid (in case of clinical clinical indication for CSF puncture)) and evaluation of regarding prognosis, course and morbidity<br>- Additional analysis of the biomaterial