NCT03940040Unknown不适用
Comparing the Effect of High Flow Nasal Oxygen With Usual Care on Pulmonary Rehabilitation in COPD Patients After an Acute Exacerbation; a Pilot Randomized Controlled Trial
适应症
干预措施
试验速览
- 阶段
- 不适用
- 入组人数
- 22
- 试验地点
- 1
- 主要终点
- 6-minute walk distance
研究概览
简要总结
To compare the effects of high flow nasal oxygen with usual care during an outpatient 6-week pulmonary rehabilitation program after hospitalization for COPD exacerbation.
详细描述
This is a pilot randomized controlled trial to compare the effects of high flow nasal oxygen with usual care during an outpatient 6-week pulmonary rehabilitation program after hospitalization for COPD exacerbation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 21 years and above
- •Known diagnosis of COPD based on history AND spirometry demonstrating post bronchodilator FEV1/FVC ratio <0.7
- •Currently admitted inpatient for an acute COPD exacerbation as the primary diagnosis
- •Fit to participate in exercise therapy as determined by both physician and physiotherapist
- •Has the mental capacity to follow instructions
- •Experience shortness of breath on exertion
- •Have decreased ability to carry out activities due to shortness of breath
- •Willing to participate in the exercise program
排除标准
- •Uncontrolled/ unstable medical conditions such as severe chronic heart failure that make exercise unsafe
- •Pulmonary disorder other than COPD
- •Physical conditions that preclude the ability to participate in exercise or may impair exercise performance.
研究组 & 干预措施
Usual Care
Active Comparator
Patients will under go usual care ( pulmonary rehabilitation on room air or with nasal oxygen supplementation)
干预措施: Usual care (Other)
High flow nasal oxygen
Experimental
Patients will undergo pulmonary rehabilitation with high flow nasal oxygen
干预措施: High flow nasal oxygen (Other)
结局指标
主要结局
6-minute walk distance
时间窗: 6 weeks
It is the maximum distance walked in 6 minutes
次要结局
- Hospital Anxiety Depression Scale(3 weeks, 6 weeks and 1 month after completion of program)
- COPD Assessment Test score(3 weeks, 6 weeks and 1 month after completion of program)
- Respiratory function test(3 weeks, 6 weeks and 1 month after completion of program)
- 6-minute walk distance(3 weeks and 1 month after completion of program)
研究者
研究点 (1)
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