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临床试验/NCT04970277
NCT04970277Unknown不适用

Efficacy of Drinking Water on Transit Time and Complete Examination Rate During Capsule Endoscopy

Shandong University1 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2021年7月18日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
120
试验地点
1
主要终点
gastric transit time

研究概览

简要总结

The aims of this study are to evaluate the effect of early drinking water after the capsule ingestion on the gastrointestinal transit and image quality of capsule endoscopy.

详细描述

Capsule endoscopy has been a significant technologic advancement that has allowed the direct examination of mucosa throughout the entire small intestine in a noninvasive fashion; and it has become the primary technique for imaging the small bowel. However, as imaging time is limited to about 8 hours, a prolonged transit of the capsule endoscope in the stomach may result in an incomplete small bowel transit (i.e. failure of the capsule to reach the cecum). Delayed transit time of stomach may be responsible for the failure of capsule endoscopy to visualize the distal portions of the small bowel, and potentially may result in the inability to identify small-bowel pathology in these areas. Previous study showed that drinking water might improve completion rate of capsule endoscopy. And bowel preparation of clear liquids may improve image quality of small bowel mucosa. The aim of this study was to assess the effect of drinking water on the transit time,completion rate and image quality of capsule endoscopy.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Other
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients aged 18-80 years undergoing capsule endoscopy

排除标准

  • Patients with suspected intestinal obstruction, intestinal diverticulum, stricture or fistula
  • previous gastric or small-bowel surgery

结局指标

主要结局

gastric transit time

时间窗: 3 months

the time between the first gastric image and the first duodenal image

small-bowel transit time

时间窗: 3 months

the imaging time of capsule endoscopy in the small bowel

次要结局

  • diagnostic yields(3 months)
  • complete examination rate of the small bowel(3 months)
  • image quality(3 months)

研究者

发起方
Shandong University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Xiuli Zuo

doctoral supervisor of Qilu Hospital gastroenterology department

Shandong University

研究点 (1)

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