Pulse Spectrum Analysis in Adult Asthmatics: Correlation With Lung Function, Asthma Control Exhaled Nitric Oxide and Metabolites in Exhaled Breath Condensate

• Conditions: Pulmonary Function; Pulse Spectrum Analysis; FeNO; Metabolites

• Registration Number: NCT01719393
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

Our hypothesis is that radial arterial pulse may reflect the severity and airway function in asthmatics. The aims of this study are to investigate the pulse spectrim of the radial artery in adult asthmatics, and evaluate its correlation with airy inflammation an lung funtion in asthmatics.

Detailed Description

The microcirculation is directly involved in the cellular matabolism and homeostasis. Our hypothesis is that radial arterial pulse spectrum may reflect the airway condition in asthmatics. The aims of this study are to investigate the pulse spectrim of the radial artery in adult asthmatics, and evaluate its correlation with lung function, asthma control status,exhaled nitric oxide, and metabolites in the exhaed breath condensates.

Study Timeline

• Status Verified: 2012-10
• Study First Submitted: 2012-10-30
• Study First Submitted QC: 2012-10-31
• Last Update Submitted: 2012-10-31
• Study Start: 2012-11
• Study First Posted: 2012-11-01
• Last Update Posted: 2012-11-01
• Primary Completion: 2013-11
• Study Completion: 2013-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Meet the diagnostic criteria of GINA guideline asthma patients

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Exclusion Criteria

• Cancer or immune impaired patients;
• pack-year smoking> 5;
• long-term ventilator-dependent patients
• Control group: 30 age matched healthy controls

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pulse spectral analysis	one year

Trial Locations

Locations (1)

National Taiwan University Hospital; 🇨🇳 Taipei, Taiwan