NCT00188487TerminatedPhase 1
MR Perfusion Imaging in Asthmatic Patients
University Health Network, Toronto1 site in 1 country80 target enrollmentStarted: September 2005Last updated:
Conditions
Trial Snapshot
- Phase
- Phase 1
- Status
- Terminated
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- The correlation of MR lung perfusion analysis with computed tomography (CT) findings and pulmonary function tests
Study Overview
Brief Summary
Asthma is a disease of small airways. Affected areas have reduced lung ventilation causing reflex vasoconstriction. MR perfusion imaging of the lungs is a sensitive method of imaging zonal lung perfusion.
Detailed Description
A cohort of 70 Asthmatic Patients and 10 controls, both sets of subjects have HRCT, MRI/A of the Thorax, and Pulmonary Function Tests to correlate the degree of pulmonary dysfunction with findings on imaging tests.
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Single Group
- Primary Purpose
- Diagnostic
- Masking
- None
Eligibility Criteria
- Ages
- 16 Years to — (Child, Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •All asthmatic patients are eligible.
Exclusion Criteria
- •Patients in whom MRI is contraindicated
Outcomes
Primary Outcomes
The correlation of MR lung perfusion analysis with computed tomography (CT) findings and pulmonary function tests
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (1)
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