Magnetic Resonance (MR) in Asthmatic Patients
Phase 1
Terminated
- Conditions
- Asthma
- Registration Number
- NCT00188487
- Lead Sponsor
- University Health Network, Toronto
- Brief Summary
Asthma is a disease of small airways. Affected areas have reduced lung ventilation causing reflex vasoconstriction. MR perfusion imaging of the lungs is a sensitive method of imaging zonal lung perfusion.
- Detailed Description
A cohort of 70 Asthmatic Patients and 10 controls, both sets of subjects have HRCT, MRI/A of the Thorax, and Pulmonary Function Tests to correlate the degree of pulmonary dysfunction with findings on imaging tests.
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
- All asthmatic patients are eligible.
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Exclusion Criteria
- Patients in whom MRI is contraindicated
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method The correlation of MR lung perfusion analysis with computed tomography (CT) findings and pulmonary function tests
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Toronto General Hospital
🇨🇦Toronto, Ontario, Canada