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Clinical Trials/NCT00188487
NCT00188487TerminatedPhase 1

MR Perfusion Imaging in Asthmatic Patients

University Health Network, Toronto1 site in 1 country80 target enrollmentStarted: September 2005Last updated:
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Conditions

Trial Snapshot

Phase
Phase 1
Status
Terminated
Enrollment
80
Locations
1
Primary Endpoint
The correlation of MR lung perfusion analysis with computed tomography (CT) findings and pulmonary function tests
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

Asthma is a disease of small airways. Affected areas have reduced lung ventilation causing reflex vasoconstriction. MR perfusion imaging of the lungs is a sensitive method of imaging zonal lung perfusion.

Detailed Description

A cohort of 70 Asthmatic Patients and 10 controls, both sets of subjects have HRCT, MRI/A of the Thorax, and Pulmonary Function Tests to correlate the degree of pulmonary dysfunction with findings on imaging tests.

Study Design

Study Type
Interventional
Allocation
Non Randomized
Intervention Model
Single Group
Primary Purpose
Diagnostic
Masking
None

Eligibility Criteria

Ages
16 Years to — (Child, Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •All asthmatic patients are eligible.

Exclusion Criteria

  • •Patients in whom MRI is contraindicated

Outcomes

Primary Outcomes

The correlation of MR lung perfusion analysis with computed tomography (CT) findings and pulmonary function tests

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other

Study Sites (1)

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