Validation of Medication Non-adherence Model (UK)

Completed

• Conditions: Chronic Illness; Medication Management at Home; Primary Care; Diabetes Mellitus; Chronic Obstructive Pulmonary Disease

• Registration Number: NCT02115412
• Lead Sponsor: Philips Healthcare

Brief Summary

Research has shown that nearly 50% of patients with chronic conditions around the globe do not adhere to their prescribed medicine, leading to enormous cost to the healthcare providers. Non-adherence can be due to various forms and have multiple causes.

To address this need, Philips Research has developed Medication Non-adherence model. This tool will help in developing a systemic way of assessing medication non-adherence and providing decision support for targeted intervention to healthcare professionals. The aim of this study is to validate this model with 750 chronically ill patients in UK.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2014-04-14
• Study First Submitted QC: 2014-04-14
• Study First Posted: 2014-04-16
• Study Start: 2014-07
• Primary Completion: 2015-12
• Study Completion: 2015-12
• Status Verified: 2020-09
• Last Update Submitted: 2020-09-25
• Last Update Posted: 2020-09-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 750

Inclusion Criteria

• Patients with chronic disease between 18 -89 years old.
• Chronic medication use (> 3 medications; excluding analgesic, ointment and eye drop medication)
• Patients registered with a given Pharmacy at least 1 year before entering into the study.

Exclusion Criteria

• Patients who are illiterate in English.
• Patients who are unable to give consent to the study.
• Enrolled in another clinical trial, which requires change in their routinely medication.
• Patients currently using automatic medication reminder services (excluding the pharmacy service).
• Patients with dementia or any other mental conditions, that might affects the accuracy of the answers provided.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Adherence determinants	6 months	Self-reported behavioral questionnaire completed at 3 monthly intervals

Secondary Outcome Measures

Name	Time	Method
Medication usage	18 months	Collecting refill data from the pharmacy where patients are registered to. Time Frame: 18 months (12 month prior to enrollment + 6 months during the study

Trial Locations

Locations (4)

Swan Lane Medical Centre; 🇬🇧 Bolton, Greater Manchester, United Kingdom

Wymondham Medical Practice; 🇬🇧 Norfolk, United Kingdom

Rosedale Surgery; 🇬🇧 Carlton Colville, Lowestoft, Suffolk, United Kingdom

Vida Health, 39 Gayton Road; 🇬🇧 King's Lynn, Norfolk, United Kingdom