aparoscopic adrenalectomy performed by a general surgeon on functioning adrenal tumors: Treatment outcomes and risk prediction of persistent hypertensio

Completed

• Conditions: Functional adrenal tumors; Adrenal cortical adenoma, Adrenalectomy, Laparoscopic surgery, Hypertension

• Registration Number: TCTR20230707007
• Lead Sponsor: /A

Brief Summary

The operative complications occurred in three patients, with one patient requiring conversion to open surgery. All of the patients were cured of hypokalemia; However, 19 patients were cured of hypertension. ASA classification and requirement for at least three medications for blood pressure control were shown to be an independent predictive factor of persistent hypertension after surgery.

Detailed Description

Not available

Study Timeline

• Study Completion: 2022-12-31
• Study Start: 2023-07-07
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

1. Patients aged 18 to 80 were included in the study.
2. Diagnosis of functional adrenal tumors included primary hyperaldosteronism, pheochromocytoma, and Cushing's syndrome.
3.Underwent laparoscopic adrenalectomy procedures at the Department of Surgery, Faculty of Medicine Srinakarinwirot University, Thailand, between January 1, 2014, and December 31, 2022

Exclusion Criteria

Patients with nonfunctional adrenal tumors, metastasized adrenal tumors, and suspected adrenal malignancies.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Postoperative outcome of laparoscopic adrenakectomy 14 days Evaluation the peri-operative complication, blood loss, Length of hospital stay

Secondary Outcome Measures

Name	Time	Method
Persistent Hypertension after surgery 30 days Systolic and diastolic blood pressures greater than 140 and 90 mmHg, respectively, after 1 month following surgery and requiring anti-hypertensive drugs for blood pressure control.