ifestyle Intervention Study for Dementia Risk Reduction in Healthy Adults Aged Over 50 Years - The LEISURE study

Not Applicable

Recruiting

• Conditions: Dementia; Neurological - Dementias

• Registration Number: ACTRN12620000054910
• Lead Sponsor: niversity of the Sunshine Coast

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-01-23
• Last Update Posted: 17 January 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

1. Individuals aged 50-85 years with a Montreal Cognitive Assessment (MoCA) score of 26 or greater;
2. Availability to complete all testing, training, and home practice requirements;
3. Normal or corrected-to-normal visual acuity;
4. Pass MRI safety checklist.

Exclusion Criteria

1. Prior head injury with loss of consciousness >60 minutes
2. Stroke or TIA.
3. Atherosclerotic cardiovascular disease.
4. Myocardial infarction (heart attack).
5. Pulmonary respiratory conditions (eg: COPD).
6. Metabolic disorders (diabetes type 1 +2; kidney disease; liver disease)
7. History of schizophrenia, bipolar, or non-affective psychiatric disorder (eg: ADHD, CFS, PTSD).
8. Major neurological condition (eg: Parkinson’s disease, Multiple sclerosis).
9. Epilepsy.
10. Current or past alcohol or other substance misuse.
11. Intellectual disability.
12. Acute psychosis.
13. Insufficient English language skills to complete standardised assessment.
14. Test results that indicate study participation is unsafe.
15. Participation in conflicting studies
16. Current or planned involvement in another lifestyle intervention program

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
HBA Dementia Risk Profile Report[Post 12-week intervention]