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Clinical Trials/NCT03143738
NCT03143738
Completed
Not Applicable

Continuous Adductor Canal Block in Comparison to Continuous Femoral Nerve Block in Patients After Total Knee Arthroplasty: Randomized Control Trail

Medical University of Lublin1 site in 1 country100 target enrollmentApril 24, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pain, Acute
Sponsor
Medical University of Lublin
Enrollment
100
Locations
1
Primary Endpoint
Morphine consumption
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

Comparison of continuous adductor canal block to continuous femoral nerve block in patients after total knee arthroplasty.

All patients will be anesthetized with spinal anesthesia. Continuous infusion of ropivacaine with a catheter implemented to the adductor canal or next to the femoral nerve.

The observed goals: pain intensity, the beginning and quality of rehabilitation.

Detailed Description

Written consent will be obtained a day before the surgery. Only subarachnoidally anaesthetised patients may participate in the study. Pencil-point spinal needle and bupivacaine (Marcaine Heavy Spinal 0.5 %) will be used. Before the beginning of operation, under ultrasound control, a catheter will be implemented to one of the chosen position: the adductor canal (the middle or lower third of thigh) or near the femoral nerve (below the inguinal ligament). The local anesthetic solution of 0.2 % ropivacaine will be started with an elastomeric pump (5 mL per hour, up to 72 hours) as soon as a catheter in the right position. The pain will be measured with VAS (visual-analogue scale) 8, 24 and 48 hours after the end of operation, and at the discharge. At the same time, i.e.: 8, 24 and 48 hours from the end of surgery, the range of flexion and extension in the operated knee will be assessed. Moreover, the possibility of patient's sitting, standing up and walking will be noted. All parameters will be reassessed before patients' discharge from the hospital. Each patient will receive paracetamol (1.0) and metamizol (1.0) intravenously (i.v.) q6h. 5 mg of morphine may be given as required, up to 2 dosages per day as a rescue medication.

Registry
clinicaltrials.gov
Start Date
April 24, 2017
End Date
July 26, 2018
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Michał Borys

associate professor

Medical University of Lublin

Eligibility Criteria

Inclusion Criteria

  • knee arthroplasty
  • obtained consent
  • subarachnoid anaesthesia

Exclusion Criteria

  • coagulopathy
  • allergy to to local anesthetics
  • depression, antidepressant drugs treatment
  • usage of painkiller before surgery
  • addiction to alcohol or recreational drugs

Outcomes

Primary Outcomes

Morphine consumption

Time Frame: 24 hours from the end of surgery

Total consumption of intravenous morphine by patients with the use of patient-controlled analgesia pump

Secondary Outcomes

  • Knee flexion(8, 24, 48 hours from the end of surgery, and at the patient discharge from the hospital (an average 4-6 days))
  • Walking(8, 24, 48 hours from the end of surgery, and at the patient discharge from the hospital (an average 4-6 days))
  • The change of acute postoperative pain(8, 24, 48 hours from the end of surgery, and at the patient discharge from the hospital (an average 4-6 days))
  • Sitting(8, 24, 48 hours from the end of surgery, and at the patient discharge from the hospital (an average 4-6 days))

Study Sites (1)

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