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Clinical Trials/NCT02355093
NCT02355093
Unknown
Phase 4

Adductor Canal Block Versus Femoral Nerve Block for Analgesia After Anterior Cruciate Ligament Reconstruction Arthroscopically

Shanghai Jiao Tong University Affiliated Sixth People's Hospital0 sites40 target enrollmentJuly 2014

Overview

Phase
Phase 4
Intervention
adductor canal block (ACB)
Conditions
Anesthesia; Reaction
Sponsor
Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Enrollment
40
Primary Endpoint
quadriceps muscle strength, as measured by handheld dynamometer.
Last Updated
11 years ago

Overview

Brief Summary

This study aims to compare continuous femoral nerve block with adductor canal block after anterior cruciate ligament reconstruction arthroscopically,especially in the effect on quadriceps strength; and to evaluate which regional anesthesia is more ideal for the patients postoperatively.

Detailed Description

Forty patients with American Society of Anesthesiologists(ASA) Ⅰ-Ⅲ(no limitation of age and gender)are randomized to receive either a continuous adductor canal block(ACB) or a femoral nerve block(FNB) via a catheter (a continuous infusion of 0.2% ropivacaine, 5 mL/h for 48 hours)in the PACU immediately after the anterior cruciate ligament reconstruction arthroscopically. Patients were under general anesthesia during the operation and received a femoral nerve block with 0.25% ropivacaine 10ml before the surgery.Both groups will receive postoperatively IV patient controlled analgesia (PCA) with morphine (bolus 0.8mg,lock-out time 15 minutes, background infusion 2ml/h)beside the continuous nerve block. Patients are going to be visited for follow-up on the day of surgery and in the following two days. Quadriceps strength is assessed with the displacement of patella.VAS at rest time、degree of knee flexion、VAS at 45°flexion of the knee、dose of opioids、whether the patient has sleep disturbance are also recorded.

Registry
clinicaltrials.gov
Start Date
July 2014
End Date
October 2015
Last Updated
11 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Responsible Party
Principal Investigator
Principal Investigator

Daqiang Zhao

Daqiang Zhao

Shanghai Jiao Tong University Affiliated Sixth People's Hospital

Eligibility Criteria

Inclusion Criteria

  • Anterior Cruciate Ligament Reconstruction

Exclusion Criteria

  • patient refusal
  • chronic use of opioids
  • coagulation disorders
  • infection at the puncture site
  • allergic to anaesthetic
  • preexisting neurological disorders
  • communication difficulties

Arms & Interventions

adductor canal block (ACB)

We performed an ultrasound survey at the medial part of the thigh,the needle is introduced in-plane and 2 to 3 mL of saline is used to ensure correct placement of the needle in the vicinity of the saphenous nerve in the adductor canal,the catheter is introduced and advanced 1 to 2 cm beyond the tip of the needle.The study medication is administered as an infusion of 0.2% ropivacaine at a rate of 5mL/h during the next 48 hours.

Intervention: adductor canal block (ACB)

adductor canal block (ACB)

We performed an ultrasound survey at the medial part of the thigh,the needle is introduced in-plane and 2 to 3 mL of saline is used to ensure correct placement of the needle in the vicinity of the saphenous nerve in the adductor canal,the catheter is introduced and advanced 1 to 2 cm beyond the tip of the needle.The study medication is administered as an infusion of 0.2% ropivacaine at a rate of 5mL/h during the next 48 hours.

Intervention: ropivacaine

Femoral nerve block (FNB)

the catheter is inserted in-plane with the probe parallel to the inguinal crease, to obtain a short-axis view of the nerve. The correct needle placement is confirmed by injecting 2 to 3 mL of saline to cause tissue expansion below the iliac fascia, lateral to the femoral artery, and in the vicinity of the femoral nerve. The catheter is introduced 1 to 2 cm beyond the tip of the needle,an infusion of 0.2% ropivacaine at a rate of 5mL/h is administered during the next 48 hours.

Intervention: Femoral nerve block (FNB)

Femoral nerve block (FNB)

the catheter is inserted in-plane with the probe parallel to the inguinal crease, to obtain a short-axis view of the nerve. The correct needle placement is confirmed by injecting 2 to 3 mL of saline to cause tissue expansion below the iliac fascia, lateral to the femoral artery, and in the vicinity of the femoral nerve. The catheter is introduced 1 to 2 cm beyond the tip of the needle,an infusion of 0.2% ropivacaine at a rate of 5mL/h is administered during the next 48 hours.

Intervention: ropivacaine

Outcomes

Primary Outcomes

quadriceps muscle strength, as measured by handheld dynamometer.

Time Frame: 3 days

Secondary Outcomes

  • pain at rest time and during flexion of the knee, as measured by visual analog score(VAS).(3 days)

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