The Impact of Pharmacist-led Mobile Application on Adherence in Chronic Kidney Disease Patients

Not Applicable

Completed

• Conditions: Adherence, Medication; Chronic Kidney Diseases
• Interventions: Other: Mobile Application

• Registration Number: NCT05168449
• Lead Sponsor: Cairo University

Brief Summary

The aim of the study is to assess the impact of pharmacist led mobile application on adherence and efficacy of medication in chronic kidney disease patients

Detailed Description

This is a prospective randomized two group pharmacist-led interventional study that will be conducted in a private nephrology clinic. The study will involve introduction of the mobile phone applications to chronic kidney disease patients to improve their adherence to the prescribed medications.

Recruited patients will be randomly divided in two groups; intervention group and control group, with baseline evaluation of outcomes to be measured.

Control group will be provided with usual care. Intervention group will be provided in addition to the usual care, with an access to the mobile application after a simple training for app usage. Both groups will be followed for a period of 3 months.

The study will include the development, validation and the testing for evaluating the specially designed mobile application.

Study Timeline

• Study First Submitted: 2021-11-24
• Study First Submitted QC: 2021-12-08
• Study First Posted: 2021-12-23
• Study Start: 2022-09-17
• Primary Completion: 2023-12-05
• Study Completion: 2023-12-05
• Status Verified: 2024-02
• Last Update Submitted: 2024-02-07
• Last Update Posted: 2024-02-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 86

Inclusion Criteria

• Stages 2-5 of chronic kidney disease
• Literate
• Ownership of android smart phone compatible with the application
• Poly-pharmacy

Exclusion Criteria

• On dialysis due to loss of kidney function
• Pregnancy due to altered physiology

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Intervention Group	Mobile Application	Intervention group will be provided in addition to the usual care, with an access to the mobile application

Primary Outcome Measures

Name	Time	Method
Change in medication adherence	Change from baseline at 3 months	Using a medication adherence questionnaire.

Secondary Outcome Measures

Name	Time	Method
Change in estimated glomerular filtration rate/ creatinine clearance	Change from baseline at 3 months	Calculated using serum creatinine lab results obtained from clinic.
Change in systolic and diastolic blood pressure	Change from baseline at 3 months	To be measured in clinic.
Change in mobile application usability and acceptability by patients	Change from baseline at 3 months	Using System Usability Scale (SUS) questionnaire. (scale 0-100 with higher score meaning better usability)
Change in HbA1c	Change from baseline at 3 months	Lab results obtained from clinic.

Trial Locations

Locations (1)

Private Clinic; 🇪🇬 Cairo, Egypt