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临床试验/NCT02795715
NCT02795715撤回不适用

Effects of Transcranial Direct Current Stimulation (tDCS) on Associative Learning in Young Adults

Charite University, Berlin, Germany2 个研究点 分布在 1 个国家开始时间: 2016年4月最近更新:
适应症

试验速览

阶段
不适用
状态
撤回
试验地点
2
主要终点
Performance in a verbal associative learning paradigm under anodal tDCS compared to sham tDCS.

研究概览

简要总结

The aim of this study is to investigate whether a tDCS-accompanied training of audio-visual associative memory leads to a performance improvement in healthy older individuals."

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Treatment
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 30 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Age: young (18-30 years)
  • Right handedness
  • unobtrusive neuropsychological screening

排除标准

  • Mild cognitive impairment (MCI) or other neurological diseases.
  • History of severe alcoholism or use of drugs.
  • Severe psychiatric disorders such as depression, psychosis (if not in remission) and severe untreated medical problems.
  • Contraindication for MRI (claustrophobia, metallic implants, ferromagnetic metals in the body, disorders of thermoregulation, pregnant women).

结局指标

主要结局

Performance in a verbal associative learning paradigm under anodal tDCS compared to sham tDCS.

时间窗: assessed immediately after training period (several learning blocks) compared to sham

Investigation whether anodal tDCS leads to improved performance accuracy in the Wernicko task compared to sham stimulation.

次要结局

  • Genotyping of learning related polymorphisms(assessed during baseline screening)
  • Structural predictors(assessed during baseline testing)
  • Other cognitive outcomes: Attention performance(assessed directly before and immediately after tDCS + training compared to sham)
  • Functional connectivity predictors(assessed during baseline testing)
  • Other cognitive outcomes: working memory performance(assessed directly before and immediately after tDCS + training compared to sham)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Agnes Flöel

Prof. Dr.

Charite University, Berlin, Germany

研究点 (2)

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