Evaluation of Metformin effect on left ventricular function and on energetic metabolism, in patients affected by heart failure and glucidic intolerance. - ND

• Conditions: patients affected by heart failure and glucidic intolerance.; MedDRA version: 9.1Level: LLTClassification code 10008908Term: Chronic heart failure

• Registration Number: EUCTR2009-010292-24-IT
• Lead Sponsor: OSPEDALE S. RAFFAELE

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-03-10
• Last Update Posted: 19 March 2012

Recruitment & Eligibility

• Status: Authorised-recruitment may be ongoing or finished
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

-patients aged between 18 and 90 years; -FE<40% tested by ECOcardio; heart failure ongoing from at least 6 months; - NYHA class II-III; -adequate medical therapy from at least 2 months;-anomalies in fasting value of glycaemia registered at baseline (>105 mg/dl).
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

patologies that may creae problems during the study (diabetes mellitus, cancer etc.); -partecipation in another clinical study;etc...

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Main Objective: to evaluate the functional and metabolic effects of metformine in patients affected by heart failure and glucidic intolerance.;Secondary Objective: to evaluate the functional and metabolic effects of metformine in patients affected by heart failure and glucidic intolerance.;Primary end point(s): evaluation of the changes in cardiac function after supply of metformin to conventional therapy for heart failure.