Study Comparing Two Types of Psychotherapy for Treating Depression and Substance Abuse

Not Applicable

Completed

• Conditions: Alcohol Abuse; Cannabis Abuse; Major Depressive Disorder; Substance-Related Disorders
• Interventions: Behavioral: Integrated Cognitive Behavioral Therapy; Behavioral: Twelve Step Facilitation Therapy

• Registration Number: NCT00108407
• Lead Sponsor: US Department of Veterans Affairs

Brief Summary

The purpose of this study is to determine whether Integrated Cognitive Behavioral Therapy or Twelve Step Facilitation Therapy is most effective for treatment of dually diagnosed veterans with depressive and substance use disorders.

Detailed Description

Depression is the most frequent co-occuring mental health disorder among adults with substance use disorders, and such comorbidity is often associated with poorer treatment outcomes. Although there is an urgent need for effective treatments specific for dual-diagnosis adults, few studies have been conducted to address this need.

Comparison: This study will compare substance use and depression symptoms of individuals in two different psychotherapy groups: Integrated Cognitive Behavioral Therapy and Twelve Step Facilitation Therapy. Symptoms and substance use will be compared during the active treatment phase (24 weeks) and for one year following the end of the active treatment.

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2004-10
• Study First Submitted: 2005-04-14
• Study First Submitted QC: 2005-04-14
• Study First Posted: 2005-04-15
• Status Verified: 2009-03
• Last Update Submitted: 2009-03-04
• Last Update Posted: 2009-03-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Individuals diagnosed with one or more substance use disorders (alcohol, cannabis, and or stimulant abuse/dependence) and an independent co-occurring depressive disorder (major depression or dysthymia) will be included.

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Exclusion Criteria

• Individuals with substance induced mood disorders and individuals experiencing persistent psychotic symptoms.
• Those with life threatening or unstable medical illness, neurological disorders, or inability to read will be excluded.
• Individuals currently prescribed steroids, disulfiram, or long acting benzodiazepines will be excluded.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	Integrated Cognitive Behavioral Therapy	Integrated Cognitive Behavioral Therapy
2	Twelve Step Facilitation Therapy	Twelve Step Facilitation Therapy

Trial Locations

Locations (1)

VA San Diego Healthcare System, San Diego; 🇺🇸 San Diego, California, United States