Integrated Intervention for Substance Abusers With Depressive Disorders

Phase 2

Completed

• Conditions: Substance-Related Disorders; Depressive Disorder

• Registration Number: NCT00018655
• Lead Sponsor: VA Office of Research and Development

Brief Summary

This study is a randomized clinical trial comparing outcomes of Integrated Cognitive Behavioral Treatment plus standard medications for veterans with both substance use disorders, depressive disorders versus the most commonly administered form of therapy for substance use disorders and depression, Twelve Step Facilitation (AA/NA model) group treatment plus medications.

Detailed Description

This study is a randomized clinical trial comparing outcomes of Integrated Cognitive Behavioral Treatment plus standard medications for veterans with both substance use disorders, depressive disorders versus the most commonly administered form of therapy for substance use disorders and depression, Twelve Step Facilitation (AA/NA model) group treatment plus medications. Follow-up assessments were conducted at quarterly intervals for one year following treatment.

Study Timeline

• Study Start: 2000-04
• Study First Submitted: 2001-07-03
• Study First Submitted QC: 2001-07-04
• Study First Posted: 2001-07-05
• Primary Completion: 2009-09
• Study Completion: 2012-09
• Status Verified: 2019-04
• Last Update Submitted: 2019-04-17
• Last Update Posted: 2019-04-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 276

Inclusion Criteria

Veterans age 18 and older with alcohol, cannabinol, and/or stimulant dependence and independent mood disorders will be included.

Exclusion Criteria

Psychotic disorders

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Primary Outcome Measures

Name	Time	Method
Hamilton Depression Scale, Timeline Follow-back (substance measure)	18 months

Trial Locations

Locations (1)

VA San Diego Healthcare System, San Diego; 🇺🇸 San Diego, California, United States