Blood Loss Quantification During Major Abdominal Surgery

• Conditions: Blood Loss, Surgical; Blood Loss, Postoperative; Postoperative Complications
• Interventions: Other: Measurement of external blood loss; Diagnostic Test: Serum Hemoglobin concentration

• Registration Number: NCT05316649
• Lead Sponsor: University of Defence, Faculty of Military Health Sciences

Brief Summary

Blood loss quantification during surgery remains unreliable and inaccurate. The purpose of the study is compare several methods of blood loss quantification in real surgical settings and to analyze the effect of blood loss on postoperative complications.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-05-01
• Status Verified: 2022-03
• Study First Submitted: 2022-03-20
• Study First Submitted QC: 2022-03-30
• Last Update Submitted: 2022-03-30
• Study First Posted: 2022-04-07
• Last Update Posted: 2022-04-07
• Primary Completion: 2022-06-30
• Study Completion: 2022-08-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

• patient scheduled for liver or pancreatic surgery
• age of patient ≥ 18 years
• signed informed consent provided

Exclusion Criteria

• patient coagulation disorder (congenital or iatrogenic due to the chronic use of anticoagulants).
• use of cell saver suctioning during operation
• damage/clotting of blood samples

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
HPB group	Measurement of external blood loss	Adult patients undergoing for elective liver or pancreas surgery at Department of Surgery, University Hospital Hradec Kralove, Czech Republic.
HPB group	Serum Hemoglobin concentration	Adult patients undergoing for elective liver or pancreas surgery at Department of Surgery, University Hospital Hradec Kralove, Czech Republic.

Primary Outcome Measures

Name	Time	Method
Blood loos quantification	1 year	Estimated blood loss by surgeon (sEBL) Estimated blood loss by anesthesiologist (aEBL) Gravimetric blood loss weighted (vGBL) Calculated blood loos based on anthropometric and hematological parameters (vCBL) Spectrophotometric measured hemoglobin mass loss (hbMBL) Measured blood loss using using hbMBL and patient's average pre- and postoperative serum hemoglobin (vMBL)

Secondary Outcome Measures

Name	Time	Method
Postoperative complications	1 year	The effect of blood loss measured by spectrophotometric method on postoperative complications.

Trial Locations

Locations (1)

University of Defence, Faculty of Military Health Sciences; 🇨🇿 Hradec Králové, Czechia