NCT03836092已完成不适用
Identification of AF Triggers, Initiators and Perpetuators by Electro Cardio-Graphic Imaging (ECGI) in Patients With Persistent Atrial Fibrillation
Pacific Rim Electrophysiology Research Institute1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2018年2月23日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Freedom from Atrial Fibrillation
研究概览
简要总结
To determine the values and limitations of ECGI in guiding ablation and risk stratification in patients with persistent atrial fibrillation.
详细描述
The patient population will include symptomatic persistent AF patients (N=50). The total of fifty patients will be studied to determine:
- The values and limitations of ECGI in identifying atrial fibrillation (AF) triggers, AF initiators and AF perpetuators as targets sites for catheter ablations in patients with persistent AF.
- The mechanisms of residual atrial tachycardia/flutter (Res-AT/AFl) after AF substrate ablations by targeting complex fractionated atrial electrograms (CFAE).
- If there is a relationship between primary CFAE sites and driver sites or other distinct patterns from the ECGI mapping system.
- The rate of AF termination to sinus rhythm after ablation at target sites identified by ECGI
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients are diagnosed as persistent AF. Persistent AF was defined as continuous AF from 7 days to 12 months and long- lasting AF beyond twelve months.
- •Patients who are symptomatic
- •Patients who are willing to sign consent and be followed post procedure in an out- patient arrhythmia clinic
排除标准
- •Patients under 18 years or over 85 years of age.
- •Patients with chronic alcoholism.
- •Recent myocardial infarction within one month of the study.
- •Significant debilitating diseases or a terminal disease.
- •Patients with documented left atrial thrombus.
- •Medical or mental conditions precluding a long-term follow-up.
结局指标
主要结局
Freedom from Atrial Fibrillation
时间窗: 1 year
termination via ablation from atrial fibrillation during follow up period
次要结局
- termination via ablation from atrial fibrillation during procedure(over 6 months)
研究者
Koonlawee Nademanee, MD
Principal Investigator
Pacific Rim Electrophysiology Research Institute
研究点 (1)
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