NCT07261761已完成不适用
Cytokines as Diagnostic Markers of Pulpal Inflammation and Their Impact on the Outcome of Vital Pulp Therapy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Clinical success
研究概览
简要总结
intervention eligible patients with teeth diagnosed with reversible or irreversible pulpits will go for vital pulp therapy and the other group will be patients will go for extraction of caries free teeth for orthodontic reasons, blood samples will be collected from both groups to analyze the level of cytokines IL-8 and IL-10 and it's relation with the success of the pulp therapy
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 16 Years 至 45 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The age ranges from 16-45 years medically free.
- •Tooth should be vital on cold testing.
- •Vital permanent premolar and molar on cold testing, with deep caries, subsequent pulp exposure and bleeding pulp tissue in all canals after complete pulpotomy.
- •Diagnosis is either reversible or irreversible pulpitis with/ without periapical rarefaction.
- •The tooth is restorable and free from advanced periodontal disease.
- •Soft tissues around the tooth are normal with no swelling or sinus tract.
排除标准
- •Patients over 45 years of age.
- •Patients with clinical symptoms of periradicular inflammation or any periradicular radiographic lesions.
- •Negative results for cold and electrical pulp testing
结局指标
主要结局
Clinical success
时间窗: one day, one, four and twelve weeks.
post operative pain on cold testing binary outcome (Yes or no)
次要结局
- Radiographic success(Pre-operative , and after six months)
- level of cytokines(through study completion, an average of 6 months)
研究者
Mohamed Khalifa
Researcher at faculty of dentistry Mansoura University
Mansoura University
研究点 (1)
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