High-resolution MRI (7 Tesla) of the Cervical Spine in Asymptomatic Individuals

Completed

• Conditions: Cervical Spine Anatomy; Magnetic Resonance Imaging; Reference Standard

• Registration Number: NCT04445584
• Lead Sponsor: Balgrist University Hospital

Brief Summary

High-resolution MRI (7 Tesla) of the cervical spine is capable to provide good differentiation between nerve and surrounding tissues within foramen und allows to reliably quantify the diameter of nerve roots/ganglia. Secondly, detailed anatomy of vertebral artery and its relation to neural structures / foramina can be assessed.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-06-01
• Study First Submitted: 2020-06-19
• Study First Submitted QC: 2020-06-23
• Study First Posted: 2020-06-24
• Primary Completion: 2022-02-01
• Study Completion: 2022-02-01
• Status Verified: 2022-08
• Last Update Submitted: 2022-08-30
• Last Update Posted: 2022-09-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Informed consent as documented by signature (Appendix Informed Consent Form)
• >18 years old
• no cervical back pain

Exclusion Criteria

• previous surgery
• tumor patients
• pregnancy or breast feeding
• any MRI contra-indications

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
standard values (diameter in mm) of nerve roots/ganglia/neuroforamen in each segment	1 year	measure the diameter of the neuroforamen (in mm) and the diameter of each cervical nerve root/ganglion within the neuroforamen (in mm)

Secondary Outcome Measures

Name	Time	Method
relation of vertebral artery to neural structures - assessment of contact between ganglion/spinal nerve and vertebral artery by assessing the presence of fat tissue between these structures.	1 year	to assess if there is contact between the vertebral artery and the ganglion/spinal nerve at each segment and each side if no fat tissue is interposed between the ganglion and vertebral artery it is classified as having contact. If contact is present, the length of contact (in mm) will be measured in the axial plane.

Trial Locations

Locations (1)

Balgrist University Hospital; 🇨🇭 Zurich, Switzerland