Effect of Drakshadi Ghritapana, Vasanjana and Anutaila Nasya on Shushkakshipaka (Dry Eye Syndrome)

Phase 2

Recruiting

• Conditions: Shushkakshipaka (Dry eye syndrome)

• Registration Number: CTRI/2013/06/003736
• Lead Sponsor: Institute for post graduate teaching and research in Ayurveda Gujarat Ayurved University Jamnagar

Brief Summary

This study is a randomized, open clinical trial. This study aims at evaluatingthe efficacy of Ayurvedic treatment protocol including Drakshadi Ghritapana,Vasanjana and Anutaila Nasya inmanagement of Shushkakshipaka i.e. Dry eye syndrome. A standard control i.e.Ecotear eye drops is being used as a comparator agent. A follow up study will be carried out for one month after completion oftreatment, subjecting to patients availability. The results will be assessed byimprovement in sign & symptoms of the disease and also based upon changesin Objective parameters.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2013-06-06
• Study Start: 2013-07-03

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• 1.Patients presenting with the symptoms suggestive of dry eye like irritation, foreign body(sandy) sensation, feeling of dryness, itching, non-specific ocular discomfort & classical symptoms of Shushkashipaka alongwith altered/effected QOL.
• 2.Patients age between 20-70 years and willing to participate in this study.
• 3.Tear film break up time less than 10 seconds.
• 4.Schirmers -1 test positive < 10 mm 5.Rose Bengal staining showing devitalized epithelium of conjunctiva and mucus plaques on the cornea.
• Any two criteria out of 3/4/5 are positive,diagnosis of dry eye syndrome is confirmed.

Exclusion Criteria

• 1.Patients not willing to participate in this study.
• 2.Severe cases of dry eye syndrome with complications like perforated corneal ulcer, Uveitis, Glaucoma.
• 3.Inflammatory conditions like acute conjunctivitis etc.
• 4.Systemic diseases causing Dry Eye Syndrome.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improvement in objective parameters like Schirmers -1 test, Rose Bengal staining, tear film breakup time, Fluorescein staining.	30 days

Secondary Outcome Measures

Name	Time	Method
No recurrence during follow up period	1 month

Trial Locations

Locations (1)

Institute for post graduate teaching and research in Ayurveda, Gujarat Ayurved University, Jamnagar.; 🇮🇳 Jamnagar, GUJARAT, India

Institute for post graduate teaching and research in Ayurveda, Gujarat Ayurved University, Jamnagar.

🇮🇳Jamnagar, GUJARAT, India

Dr K S Dhiman

Principal investigator

02882541413

dr_ks_dhiman@yahoo.co.in