Feasibility study of Neoadjuvant chemoradiotherapy for locally advanced esophageal carcinoma
- Conditions
- Esophageal Cancer
- Registration Number
- JPRN-UMIN000004223
- Lead Sponsor
- ational Cancer Center Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 60
Not provided
1)active other malignancies within 5 years 2)Pregnant or lactating women, women who are capable of pregnancy or intend to get pregnant, men who don't intend to have protected intercourse. 3)Unsuitable mental status and condition for clinical trials. 4)Patients who received ontinuous steroids (orally or intravenous) administration. 5)Positive HBsAg. 6)Unstable diabetes mellitus with oral hypoglycemic agent or insulin. 7)Acute myocardial infarction within 3 months 8)severe complications (COPD, interstitial lung disease, pulmonary fibrosis, heart failure and so on) 9)clinically significant infectious disease(body temperature less than 38.0 degrees) 10)Any other cases who are regarded as inadequate for study enrollment by the investigator.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Completion proportion of curative surgery
- Secondary Outcome Measures
Name Time Method Overall survival, Progression free survival, curative resection rate, Response rate for CRT Pathological CR rate Acute toxicity Late toxicity Surgical toxicity