A feasibility study of neoadjuvant chemotherapy with mFOLFOX6 in patients with locally metastatic rectal cancer

Not Applicable

Recruiting

• Conditions: rectal cancer

• Registration Number: JPRN-UMIN000003428
• Lead Sponsor: Toho University school of medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-04-01
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Not provided

Exclusion Criteria

1.Transfusion, blood products, and G-CSF within 14 days before egistration 2.History of serious drug hypersensitivity or allergy 3.Multiple malignancies 4.Uncontrolled complication of pleural, ascites and pericardium fluid 5.Infection 6 Current or previous brain and bone metastasis 7.Serious heart disease such as congestive heart failure, symptomatic coronary artery disease, uncontrolled arrhythmia 8.Serious hepatic toxicit, pulmonary complaints(interstitial pneumonia) 9.Serious dysesthesia 10.Diarrhea 11.Intestinal paralysis and intestinal obstruction 12.Evidence of psychiatric disability interfering with enrollment to clinical trial 13.Uncontrolled diabetic 14.With atazanavir sulfate. 15.With TS-1 16.Pregnancy 17.Patients judged inappropriate for this study by physicians

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
OS, DFS

Secondary Outcome Measures

Name	Time	Method
Pathological effect, Down stgaging