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Clinical Trials/NCT06247891
NCT06247891
Completed
Not Applicable

Endocytoscopy of Upper Gastrointestinal Tract in Acute Graft-versus-host Disease: a Pilot Study

Ruijin Hospital1 site in 1 country14 target enrollmentAugust 1, 2021
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ConditionsEndocytoscopy

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Endocytoscopy
Sponsor
Ruijin Hospital
Enrollment
14
Locations
1
Primary Endpoint
the effectiveness of endocytoscopy for diagnosing UGI aGvHD
Status
Completed
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The goal of this clinical trial is to test the assess the diagnostic effectiveness of endocytoscopy in patients with underlying UGI aGvHD. The main question it aims to answer is: the effectiveness of ECS for diagnosing UGI aGvHD. Participants will undergo endoscopy, endocytoscopic evaluation and biopsy simultaneously. If there is a comparison group: Researchers will compare endoscopic, endocytoscopic and pathologic findings of these patients.

Registry
clinicaltrials.gov
Start Date
August 1, 2021
End Date
November 30, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • •aged ≥ 14 years
  • •developed UGI symptoms within first three months after engraftment or during the tapering of immunosuppressive agents

Exclusion Criteria

  • •\< 14 year
  • •with underlying gastrointestinal disease before allo-HSCT
  • •incomplete medical information

Outcomes

Primary Outcomes

the effectiveness of endocytoscopy for diagnosing UGI aGvHD

Time Frame: three months

the percentage of esophageal, gastric, and duodenal UGI aGvHD diagnosed by endocytoscopy

Study Sites (1)

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