Post-resuscitation Care Registry for Survival From Out-of-hospital Cardiac Arrest

Completed

• Conditions: Out-Of-Hospital Cardiac Arrest

• Registration Number: NCT03695718
• Lead Sponsor: Seoul National University Hospital

Brief Summary

The aim of this study is to construct multi-center post-cardiac arrest care registry that can be used for data warehousing and clinical research.

Detailed Description

This registry prospectively enrolls adults patients survived out-of-hospital cardiac arrest in 3 academic hospital emergency departments.

Registered data can be used for quality control and clinical research to reduce post-cardiac arrest syndrome-related mortality.

Study Timeline

• Study Start: 2013-12-03
• Study First Submitted: 2018-06-08
• Study First Submitted QC: 2018-10-02
• Study First Posted: 2018-10-04
• Primary Completion: 2019-12-31
• Study Completion: 2020-06-30
• Status Verified: 2022-02
• Last Update Submitted: 2022-02-16
• Last Update Posted: 2022-02-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1057

Inclusion Criteria

• Patients aged 20 years old or older who presents to the ED of the participating hospitals with any of the following criteria:

  1. Sustained ROSC from OHCA at pre-hospital level
  2. Sustained ROSC from OHCA at the ED of the participating hospitals after ACLS
  3. Patients sustained ROSC from OHCA and transferred from other hospital to the ED of the participating hospitals for post-cardiac arrest care

Exclusion Criteria

• Age less than 20 years old
• Patients with advanced directives not to deliver aggressive organ supportive management

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Survival	1-year	One year survival

Secondary Outcome Measures

Name	Time	Method
1-year CPC	1-year	Brain function at 1-year
Organ support treatment (renal replacement therapy)	Hospital discharge (non-survivors) or 1-year (survivors)	Renal replacement therapy
Organ support treatment (mechanical ventilation)	Hospital discharge (non-survivors) or 1-year (survivors)	Mechanical ventilation
28-day mortality	28-day	Mortality on the 28th day
28-day CPC	28-day	Brain function at 28th day
6-month CPC	6-month	Brain function at 6-month
ICU length of stay	Hospital discharge (non-survivors) or 1-year (survivors)	ICU length of stay
Hospital length of stay	Hospital discharge (non-survivors) or 1-year (survivors)	Hospital length of stay

Trial Locations

Locations (3)

Seoul National University Boramae Hospital; 🇰🇷 Seoul, Korea, Republic of

Seoul National University Bundang Hospital; 🇰🇷 Seongnam-si, Korea, Republic of

Seoul National University Hospital; 🇰🇷 Seoul, Korea, Republic of