NL-OMON39548
Completed
Not Applicable
Feasibility study of biomarker development for response prediction by large scale DNA mutational analysis of metastatic lesions. - CPCT - 01 trial
niversitair Medisch Centrum Utrecht0 sites80 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- metastatic cancer
- Sponsor
- niversitair Medisch Centrum Utrecht
- Enrollment
- 80
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Metastatic colorectal carcinoma or other solid tumors
- •Failed at least one line of palliative chemotherapy
- •Irinotecan naïve
- •Eligible, as per local protocol, for palliative treatment with standard of care irinotecan
- •Measurable metastatic lesion(s) according to RECIST 1\.1\. criteria
- •Safe biopsy of a radiological measurable lesion possible
- •Adults age 18 years or up
- •Written informed consent
Exclusion Criteria
- •Patients with other malignancies than metastatic colorectal cancer or other solid tumors
- •Patients eligible for first\-line treatment
- •Patients who were already subjected to treatment with irinotecan
- •Patients with disease not measurable according to RECIST 1\.1\. criteria
- •Safe biopsy of radiological measurable lesion not possible
- •Patients younger than 18 years old
- •Patients not willing to sign informed consent
Outcomes
Primary Outcomes
Not specified
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