Deep vs Moderate Neuromuscular Blocks on Remifentanil for Laparoscopic Gastrectomy
Not Applicable
Completed
- Conditions
- Gastric Cancer
- Interventions
- Registration Number
- NCT04205097
- Lead Sponsor
- Ajou University School of Medicine
- Brief Summary
The primary purpose is to compare the remifentanil requirements in deep vs moderate neuromuscular blocks during the surgical pleth index -guided anesthesia in patients undergoing laparoscopic gastrectomy.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
- Clinical diagnosis of gastric cancer Scheduled laparoscopic gastrectomy
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Exclusion Criteria
- Patients refusal to consent Hyperbilirubinemia Chronic pain Opioid abuse Incurrent infective status Peripheral vascular disease
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Moderate NMB group Neostigmine + glycopyrate maintaining of moderate neuromuscular block (train-of-four count 1-2) during surgery, reversal using neostigmine 50 ug/kg and glycopyrrolate 10 ug/kg Deep NMB group Sugammadex maintaining of deep neuromuscular block (posttetanic count 1-2) during surgery, reversal using sugammadex 2\~4 mg/kg
- Primary Outcome Measures
Name Time Method total dose of remifentanil from pneumoperitoneum to removal of laparoscope remifentanil infusion using target effect-site concentration to achieve an surgical pleth index of range between 20 and 50
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine
🇰🇷Suwon, Gyeonggido, Korea, Republic of