Comparison of Deep Neuromuscular Block and Moderate Neuromuscular Block on Quality of Recovery in Patients Undergoing Robotic Gastrectomy

Not Applicable

Completed

• Conditions: General Anesthesia
• Interventions: Drug: Deep neuromuscular blockade; Drug: Moderate neuromuscular blockade

• Registration Number: NCT02762890
• Lead Sponsor: Yonsei University

Brief Summary

The purpose of this study is to investigate and compare the postoperative quality of recovery between the deep neuromuscular blockade and moderate neuromuscular blockade during robotic gastrectomy.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2016-05-04
• Study First Submitted QC: 2016-05-04
• Study First Posted: 2016-05-05
• Study Start: 2016-10-06
• Primary Completion: 2017-02-27
• Study Completion: 2017-02-27
• Status Verified: 2017-12
• Last Update Submitted: 2017-12-15
• Last Update Posted: 2017-12-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 56

Inclusion Criteria

• adult patients aged 19-80 years who are scheduled for robotic gastrectomy

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Exclusion Criteria

• Neuromuscular disease
• History of malignant hyperthermia
• Significant renal or hepatic dysfunction
• Allergy to sugammadex or rocuronium

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Deep neuromuscular blockade	Deep neuromuscular blockade	Rocuronium will be administered continuously to achieve post-tetanic count 1-2 during surgery.
Moderate neuromuscular blockade	Moderate neuromuscular blockade	Rocuronium will be administered continuously to achieve Train-of-four 1-2 during surgery.

Primary Outcome Measures

Name	Time	Method
Postoperative quality of recovery	within 48 hours after the end of surgery.	The postoperative quality of recovery will be evaluated at 24 and 48 hours after the end of surgery by the investigator who are blinded to the group assignments.

Secondary Outcome Measures

Name	Time	Method
Surgical condition	within 48 hours after the end of surgery	Surgical condition will be evaluated after the end of surgery by the investigator who are blinded to the group assignments.
shoulder pain	within 48 hours after the end of surgery	shoulder pain will be evaluated after the end of surgery by the investigator who are blinded to the group assignments.
abdominal pain	within 48 hours after the end of surgery	abdominal pain will be evaluated after the end of surgery by the investigator who are blinded to the group assignments.
nausea and vomiting	within 48 hours after the end of surgery	nausea and vomiting will be evaluated after the end of surgery by the investigator who are blinded to the group assignments.

Trial Locations

Locations (1)

Department of Anesthesiology and Pain Medicine Anesthesia and Pain Research Institute Yonsei University; 🇰🇷 Seoul, Korea, Republic of