The efficacy of ondansetron as an adjunct to lidocaine compared with lidocaine pretreatment in reducing pain on propofol injection: A randomized controlled trial
Not Applicable
Recruiting
- Conditions
- Pain on propofol injectionAnaesthesiology - Pain management
- Registration Number
- ACTRN12624000248561
- Lead Sponsor
- King Chulalongkorn Memorial Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 260
Inclusion Criteria
ASA classification I-II
-scheduled for elective surgery with general anesthesia
-Age 18- 60 years old
-Weight more than 50 kg.
-cooperate and able to communicate
Exclusion Criteria
-patient's refusal
-did not use propofol as induction agent
-IV catheter 20G can't be accessed
-local infection at IV site
-Allergic to ondansetron or lidocaine
-History of cardiac arrhythmia
-unable to assess the pain score
-chronic pain or receive analgesic 24 hours before surgery
-RSI technique was used
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain on propofol injection [McCririck and Hunter Pain Scale immediately after injection of propofol]
- Secondary Outcome Measures
Name Time Method Pain on propofol injection [McCririck and Hunter Pain Scale 20 seconds after injection of propofol];adverse effects of ondansetron [observe EKG if there is QT prolong, observe skin reaction if there is rash. After injection until leave PACU];adverse effects of lidocaine [observe EKG for bradycardia or arrhythmia, rash on skin After injection until leave PACU]