Use of Air Purification Devices in the Homes of Children and Young People to Improve Respiratory Health - a Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- FEV1:FVC
研究概览
简要总结
The goal of this pilot study is to investigate if installing an air purifier in the homes of children and young people with asthma improves their asthma outcomes.
The main questions it aims to answer are:
- Does installing an air purifier in the homes of children and young people with asthma improve their asthma outcomes
- Is the use of an air purifier in the home acceptable to children and young people and their families?
Children and young people with asthma attending our clinic will be selected at random to be invited to take part. For those that take part, an air purifier (Rensair Ltd. - Rensair Compact) will be installed in their home for a one-year period. Data will be collected on numbers of asthma attacks, rescue oral steroids, quality of life, symptoms, lung function at the beginning and at three-monthly intervals throughout the study period. The acceptability to children and young people and their families taking part in this study of using an air purifier in their home will also be assessed.
详细描述
The goal of this pilot study is to investigate if installing an air purifier in the homes of children and young people with asthma improves their asthma outcomes.
The main questions it aims to answer are:
- Does installing an air purifier in the homes of children and young people with asthma improve their asthma outcomes (including reduction in asthma exacerbations, improvement in symptom control, improvement in quality of life).
- Is the use of an air purifier in the home acceptable to children and young people and their families?
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 5 Years 至 15 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Aged 5 to 15 years old
- •Attend the asthma clinic in our hospital
- •Have a confirmed physician-diagnosis of asthma from the asthma clinic
- •Live in mainland England (this is due to delivery of the air purification units and also associated maintenance of them)
排除标准
- •Nil specific other than not meeting inclusion criteria
结局指标
主要结局
FEV1:FVC
时间窗: 12 months
Spirometry measurements using ERS/ATS criteria and Global Lung Initiative Reference z-score
Asthma control test score
时间窗: 12 months
Asthma control test (ACT) or child asthma control test score (cACT) - depending on age of participant - the higher the score the better the asthma control
Number of parent/carer work days missed due to their child's asthma
时间窗: 12 months
Number of work days missed due to child's asthma - assessed by questionnaire
Quality of life - mini paediatric asthma quality of life questionnaire score
时间窗: 12 months
Quality of life using mini paediatric asthma quality of life questionnaire - the higher the score the better the quality of life
Amount of asthma reliever medication use per week
时间窗: 12 months
Amount of use of asthma reliever medication use over a one week period (assessed as a categorical value)
Measurement of fraction of exhaled nitric oxide (FeNO)
时间窗: 12 months
Fraction of exhaled nitric oxide measurements
Forced expired volume in one second (FEV1)
时间窗: 12 months
Spirometry measurements using ERS/ATS criteria and Global Lung Initiative Reference z-score
Number of asthma exacerbations (asthma attacks)
时间窗: 12 months
Asthma attacks and unscheduled healthcare visits due to acute asthma (including ED attendance, admission, GP/primary care attendance) - assessed by questionnaire and hospital-recorded attendances/admissions
Number of rescue oral steroid courses
时间窗: 12 months
Number of rescue oral steroid courses - assessed by questionnaire and prescription data
Number of school days absent due to asthma
时间窗: 12 months
Number of school days missed due to asthma - assessed by questionnaire
Forced vital capacity (FVC)
时间窗: 12 months
Spirometry measurements using ERS/ATS criteria and Global Lung Initiative Reference z-score
Acceptability to children and families participating of using an air purifier in their home
时间窗: 12 months
Acceptability to children and young people and their families taking part in the study in terms of use of air purifier in their homes - assessed by questionnaire
次要结局
未报告次要终点