Schistosomiasis/bilharziasis in preschool and school children along shores and on islands of Lake Victoria western Kenya: identifying suitable markers for monitoring the progress of bilharzia treatment

Not Applicable

• Conditions: Schistosomiasis; Infections and Infestations; Schistosomiasis [bilharziasis]

• Registration Number: ISRCTN12844825
• Lead Sponsor: European & Developing Countries Clinical Trials Partnership

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-05-10
• Last Update Posted: 23 May 2022
• Study Completion: 2023-05-30

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 528

Inclusion Criteria

1. Children enrolled in ECDs (PP1) and grade 4 in primary schools within Mbita Health and Demographic Surveillance System (HDSS), western Kenya
2. They should have stayed within the study site for the last 2 years and intend to stay for at least 2 more years

Exclusion Criteria

Those registered with other schistosomiasis studies

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> 1. Fecal occult blood (FOB) measured by point of care (POC) chromatographic test assessed before and after praziquantel treatment at baseline, 6 months post-baseline and end-line<br> 2. Eosinophil cationic protein (ECP) in stool measured by ELISA assessed before and after praziquantel treatment at baseline, 6 months post-baseline and end-line<br>

Secondary Outcome Measures

Name	Time	Method
Hemoglobin levels measured by POC Hemocue machine before and after praziquantel treatment at baseline, 6 months post-baseline and end-line