Investigation of the efficacy of a herbal topical gel in reducing the skin reactions in cancer patients taking chemotherapy drugs
Phase 1
- Conditions
- Hand and Foot Syndrome.Localized skin eruption due to drugs and medicaments
- Registration Number
- IRCT2015042116518N2
- Lead Sponsor
- Pharmaceutical Sciences branch, Islamic Azad University(a part of Elnaz Karimi's PharmD thesis)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Taking 5-fluorouracil (5-fu) by injection or oraly Capecitabine as an anticancer drug; showing hand-foot syndrome; patient satisfaction; Having cancer.
Exclusion criteria: Treatment change and discontinuing 5-fluorouracil (5-fu) and oral Capecitabine administration; Showing no hand-foot syndrome; Patient's death; Lack of cancer; Sensitivity to compounds of formula.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of HFS symptoms. Timepoint: Beginning of the study , the fourteenth day. Method of measurement: NCI Hand-Foot Syndrome staging version 4.0.
- Secondary Outcome Measures
Name Time Method Skin Sensitivity. Timepoint: From the beginning of the study. Method of measurement: Observational.