Assessment of Collagen Plug Versus Free Gingival Graft for Alveolar Socket Sealing With Simultaneous Implant Placement in Maxillary Esthetic Zone
试验速览
- 阶段
- 不适用
- 入组人数
- 20
- 主要终点
- changes in soft tissue
研究概览
简要总结
Following tooth extraction alveolar ridge will undergo dimensional changes and soft tissue may collapse. These changes may complicate the subsequent restorative procedure especially in the esthetic zone.
It was observed that socket-healing process may be divided into three sequential, and frequently over-lapping phases: inflammatory, proliferative and modeling/remodeling.
Implants placed in fresh extraction sockets alone wasn't found to prevent the resorption of the alveolar bone.
详细描述
Alveolar socket preservation using primary flap closure technique utilizing free gingival graft in conjunction with bone substitutes didn't produce the desired effect on ridge preservation compared with bone substitutes alone. A clinical trial showed that achieving primary closure didn't present additional beneficial effect on preserving ridge width, however, the mucosa was significantly thicker and more coronally positioned.
Also soft tissue graft has its limitations on covering graft material and socket preservation due to the higher morbidity given that the soft tissue graft has to be harvested from a donor site of the patient.
Another options for socket seal are coronal advancement of buccal flap or rotating grafts from tissue adjacent to cover the defect but they have limitations such as altering the mucogingival line and creating a shallow vestibule.
Lekovic et al. investigated the use of a non-resorbable polytetrafluroethylene membrane but it was found also to have its limitations as 30% of the membranes became exposed and as a result loss of bone height and width occurred.
Also studies have found that using bone substitutes together with collagen membrane with primary closure of the socket has shown clear effects on preserving alveolar ridge height as well as ridge width, however, its limitation are flap dehiscence and subsequent membrane exposure and the increased cost.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 25 Years 至 60 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with maxillary teeth in the esthetic zone (incisors/premolars) requiring extractions.
- •Both sexes.
- •No intraoral soft and hard tissue pathology.
- •No systemic condition that contraindicate implant placement.
排除标准
- •Uncontrolled periapical infections
- •Heavy smokers more than 20 cigarettes per day.
- •Patients with systemic disease that may affect normal healing.
- •Psychiatric problems
- •Disorders to implant are related to history of radiation therapy to the head and neck neoplasia, or bone augmentation to implant site
- •Immunodeficiency pathology, bruxism, stress situation (socially or professionally), emotional instability, and unrealistic aesthetic demands.
研究组 & 干预措施
collagen plug
collagen plug used to seal the socket after atraumatic extraction of the badly deacayed teeth with immediate implant placement and bone graft
干预措施: free gingival graft (Procedure)
结局指标
主要结局
changes in soft tissue
时间窗: 3 month
soft tissue changes will be measured in millimeters clinically and on a cast before and after the procedure
changes in bone
时间窗: 6 month
bone loss and gain will be measured in millimeters using cone beam computed tomography before and after the procedure
次要结局
未报告次要终点
研究者
sara elsandouby
principal investigator
Cairo University
