Glycemic Index of biscuit (celevida)

Not yet recruiting

Conditions: With normal BMI

Registration Number: CTRI/2024/02/063134

Lead Sponsor: Madras Diabetes Research Foundation

Brief Summary: Research studies have shown thatlifestyle; in particular dietary aspects play an important role in preventing /increasing the burden of the chronic diseases. Dietary habits could thereforebe modified to exert a positive impact in the prevention and treatment. It hasbeen suggested that the high glycemic carbohydrate foods -those foodscontaining carbohydrates which elicit rapid blood glucose rise and therebyincrease the insulin demand leading to hyperinsulinemia, insulin resistance andtype 2 diabetes. Hence, there is a need to understand the blood glucose raisingpotential of foods in India to be of an important tool to aid in the preventionand or management of diabetes and its complication. Thus, evolved the conceptof â€˜Glycemic Indexâ€™ (GI) which ranks the foods, based on the speed at which thefood raises the blood glucose in a scale of 0 to 100, 100 indicating highglycemic index corresponds to oral glucoseâ€™s GI. Today, India leading the worldwith the largest number of diabetic participants causing a heavy economicburden to the country urgently needs to look at cost effective strategies tocombat this situation. A cost-effective dietary approach like estimating andunderstanding the role of glycemic index of various Indian foods in thelifestyle related diseases like diabetes is urgently needed.

**Aim**: To measure glycemic index(GI) of celevida biscuits.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 15

Inclusion Criteria

Age 18 to 45 years BMI greater than equal to 18.5 to less than equal to 22.9 kg/ m2 (as per WHO cut offfor normal BMI) Both male and female Willingness to consume the test foods no known food allergy or intolerance; no medications known to affect glucose tolerance (excluding oral contraceptives) â€”stable doses of oral contraceptives, acetylsalicylicacid, thyroxin, vitamins and mineralsupplements or drugs to treat hypertension or osteoporosis are acceptable.

Exclusion Criteria

a known history of diabetes mellitus or the use of anti-hyperglycemic drugs or insulin totreat diabetes and related conditions pregnant or lactating women a major medical or surgical event requiring hospitalization within the preceding 3months; the presence of disease or drug(s) which influence digestion and absorption of nutrients; the use of steroids, protease inhibitors or antipsychotics (all of which have major effectson glucose metabolism and body fat distribution).

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Glycemic index,Glycemic Response and GI category of food products.	Glycemic index testing of all foods will be done on separate days. For both intervention and comparator agents capillary blood samples will be collected at -5,0 (fasting state) and at 15,30,45,60,90,120 mins from the first sip of test and reference foods.

Secondary Outcome Measures

Name	Time	Method

Trial Locations

Locations (1): Madras Diabetes Research Foundation
🇮🇳
Chennai, TAMIL NADU, India
Madras Diabetes Research Foundation
🇮🇳Chennai, TAMIL NADU, India
Dr V Mohan
Principal investigator
9840014480
drmohans@diabetes.ind.in