Refinement and Assessment of New MRI Technologies for Thoracic/ Cardiovascular Exams
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- New MRI Technologies
研究概览
简要总结
The purpose of the study is to improve chest MRI exams, eventually resulting in improvements in patient care.
详细描述
We will recruit patients to participate in the assessment of new MRI technologies designed to improve chest MRI exams that will result in improvements in patient care.
Several different MRI technologies will be evaluated. Specific evaluation of distinct technologies (eg. new head coil design, and new imaging sequence for the spine) may be evaluated simultaneously, or over non-overlapping periods in time.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •If you are a male or a non-pregnant female patient, age 18 years or older, of any ethnic background presenting to MRI for a clinically-ordered chest MRI exam, you are eligible to participate in this study.
- •If you are a female of child bearing potential you will be questioned for the possibility of pregnancy. Pregnancy screening, if necessary, is performed routinely by ordering physicians prior to MRI scanning to confirm the patient is not pregnant.
排除标准
- •Patients who have electrically, magnetically or mechanically activated implants such as heart pacemaker, magnetic surgical clips, prostheses or implanted neurological stimulator.
- •Pregnant patients or patients who are nursing
- •Patients who are claustrophobic.
研究组 & 干预措施
Group 2 - Research MRI
Subjects will have additional sequences and/or modification to MRI sequences.
干预措施: MRI-Research (Procedure)
Group 1 - Clinical MRI
Clinically ordered MRI scan. Subjects will not have any additional sequences or modifications to their clinically ordered MRI
干预措施: MRI -Clinical (Procedure)
结局指标
主要结局
New MRI Technologies
时间窗: 3 years
Assessment of the new technologies will be quantified by a variety of performance and image quality/content measures. The appropriate set of measures will be selected based on specific features offered by each assessed technology, but will be drawn from the following quantities: 1. Scan speed: Scan speed is time required to set-up and run the new technique relative to the standard method. 2. Signal to noise: SNR (signal to noise ratio)is the ratio of average image intensity in target tissue relative to standard deviation of background areas (outside of body). This is a fundamental parameter used to quantify relative performance of new imaging sequences/hardware/software. 3. Contrast to noise: CNR (contrast to noise)is the difference in average image intensity between two target tissues relative to noise. This is a key descriptor to quantity lesion/tissue conspicuity, thus is used to characterize relative performance of new imaging sequence/hardware/software.
次要结局
未报告次要终点
研究者
Jadranka Stojanovska, M.D., M.S.
Principal Investigator
University of Michigan