NL-OMON44292已完成不适用
Innovative MRI techniques to improve treatment stratification of patients with Esophageal cancer: an optimization and pilot study - IMPROVE
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Volunteers:
- •Written informed consent.;Patients:
- •Patients with biopsy proven esophageal cancer (squamous cell carcinoma or adenocarcinoma).
- •Suspected nodal involvement on EUS or CT at diagnosis.
- •WHO-performance score 0-2.
- •Scheduled for surgery.
- •Written informed consent.
排除标准
- •Any psychological, familial, sociological or geographical condition potentially hampering adequate informed consent or compliance with the study protocol.
- •Contra-indications for MR scanning, including patients with a pacemaker, cochlear implant or neurostimulator; patients with non-MR compatible metallic implants in their eye, spine, thorax or abdomen; or a non-MR compatible aneurysm clip in their brain; patients with severe claustrophobia.
- •Active inflammatory diseases
- •History of anaphylaxis or other hypersensitivity reactions
- •History of iron overload
- •History of abnormal liver function, or elevated liver enzymes (ALAT, ASAT > 3 times upper limit of normal)
- •Elevated Serum Transferrin Saturation (TSAT) (>50%) or hemoglobin (>10.5mmol/L)
- •Deminished kidney function (eGFR<60)
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