NL-OMON53657
Recruiting
Not Applicable
Advanced MRI techniques and biomarkers to substitute gadolinium enhanced MRI for the detection of disease activity in multiple sclerosis. - ACTIVITY
Amsterdam UMC0 sites75 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Multiple Sclerosis
- Sponsor
- Amsterdam UMC
- Enrollment
- 75
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •To be eligible for this study, the participant must meet the following
- •Diagnosed as CIS, RRMS, PPMS based on McDonald criteria (2017\)
- •Adult (18\-70 years old)
- •Signed informed consent
- •Separate inclusion criteria will be applied for the active and inactive
- •For the active subgroup:
- •one or more Gd\-enhancing lesion on brain MRI or signs of clinical disease
- •For the inactive subgroup:
- •no Gd enhancing lesion on brain MRI and no clinical signs of disease activity.
Exclusion Criteria
- •A potential participant will be excluded from the study based on the following
- •contra\-indications for MRI
- •History of (psychiatric) disorder which causes the patient to be incompetent to
- •make a well\-informed decision
- •Other concurrent neurological disease
Outcomes
Primary Outcomes
Not specified
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