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Clinical Trials/NL-OMON55072
NL-OMON55072RecruitingNot Applicable

eurological MRI-based biomarkers for treatment navigation in depression - Neurotrend

Technische Universiteit Eindhoven0 sites180 target enrollmentStarted: TBDLast updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Recruiting
Enrollment
180

Study Overview

Brief Summary

No summary available.

Study Design

Study Type
Observational

Eligibility Criteria

Ages
18 to 64 (—)

Inclusion Criteria

  • Satisfy DSM-5 clinical criteria for MDD (Only acute and subacute duration
  • (0-2 years), for MDD group only)
  • Unipolar depression (i.e. no bipolar disorder/mania, for MDD group only)
  • Age: 18-65 (m/f)
  • Willing and able to provide informed consent and agree that incidental
  • findings are reported

Exclusion Criteria

  • Concurrent neurological disorders (e.g. epilepsy, stroke, head trauma, etc.)
  • Current substance or alcohol abuse
  • History of psychosis, bipolar depression, autism spectrum disorder, attention
  • deficit hyperactivity disorder or (mild) intellectual disability
  • Contra-indication for MRI: implants, tattoos non-compatible with brain MRI,
  • pregnancy, claustrophobia
  • Current or previous treatment with electroconvulsive therapy (ECT),
  • deep-brain stimulation (DBS) or transcranial magnetic stimulation (TMS)
  • More than 3 depressive episodes in the past (for MDD group only)
  • Has a current episode of MDD or ever had an MDD episode (for healthy control
  • group only)

Investigators

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