NL-OMON55072
Recruiting
Not Applicable
eurological MRI-based biomarkers for treatment navigation in depression - Neurotrend
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Major Depressive Disorder
- Sponsor
- Technische Universiteit Eindhoven
- Enrollment
- 180
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Satisfy DSM\-5 clinical criteria for MDD (Only acute and subacute duration
- •(0\-2 years), for MDD group only)
- •Unipolar depression (i.e. no bipolar disorder/mania, for MDD group only)
- •Age: 18\-65 (m/f)
- •Willing and able to provide informed consent and agree that incidental
- •findings are reported
Exclusion Criteria
- •Concurrent neurological disorders (e.g. epilepsy, stroke, head trauma, etc.)
- •Current substance or alcohol abuse
- •History of psychosis, bipolar depression, autism spectrum disorder, attention
- •deficit hyperactivity disorder or (mild) intellectual disability
- •Contra\-indication for MRI: implants, tattoos non\-compatible with brain MRI,
- •pregnancy, claustrophobia
- •Current or previous treatment with electroconvulsive therapy (ECT),
- •deep\-brain stimulation (DBS) or transcranial magnetic stimulation (TMS)
- •More than 3 depressive episodes in the past (for MDD group only)
- •Has a current episode of MDD or ever had an MDD episode (for healthy control
Outcomes
Primary Outcomes
Not specified
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