Evaluation and comparison of Ozonated water and Ozonated Olive oil as an adjunct to non surgical periodontal therapy: A Randomized Controlled Clinical Trial.
试验速览
- 阶段
- Phase 3 4
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Probing Pocket Depth Reduction
研究概览
简要总结
Most cases of slight and moderate chronic periodontitis can be successfully managed by mechanical removal and/or reduction of subgingival bacterial biofilms and calculus. The most popular and clinically established periodontal therapy is scaling and root planing (SRP). However, there are several drawbacks to SRP. Ozone, is a naturally occurring molecule made up of three oxygen atoms. Because of its great antibacterial activity without causing medication resistance, ozone is presently being considered as a potential substitute antiseptic agent in dentistry Ozone treatment may be administered in a variety of ways, the most popular being gas and aqueous - Ozonated water and Ozonated Olive Oil.
Therefore, the current study aims to assess and compare the efficacy of ozonated water and ozonated olive oil as supplemental to non-surgical treatments for chronic periodontitis. A total of 30 systemically healthy patients with chronic periodontitis will be treated with ozonated water (Group-A) and ozonated olive oil (Group-B). Assessments of clinical parameters will be done at baseline, 1 months and 3 months. Statistical analysis will be performed on the resulting data.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
入排标准
- 年龄范围
- 30.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients motivated to have the therapy and complete follow up.
- •Subjects who readily give informed consent for the study.
- •Patients with a minimum number of 15 teeth.
- •Good physical and systemic health.
- •Patients with clinical attachment loss more than or equal to 1 mm .
- •Chronic generalized periodontitis with at least 2-3 sites exhibiting periodontal pockets with depths more than or equal to 4mm will be selected for the study.
排除标准
- •Patients who have undergone periodontal therapy in last 6 months.
- •Patients who had received antibiotic therapy during the previous three months.
- •Individuals who are expecting or who have allergies to the drugs in study.
- •Pregnant ladies and lactating mothers .
- •Regular users of mouthwash.
- •Chronic alcoholics.
结局指标
主要结局
Probing Pocket Depth Reduction
时间窗: baseline, post-operatively 1 month, 3 months
次要结局
- Clinical Attachment Level Gain(baseline, post-operatively 1 month, 3 months)
研究者
Dr Sakshi Kotecha
Sharad Pawar Dental College