Treating Alzheimer's and Dementia With D-ribose

Not Applicable

Terminated

• Conditions: Alzheimers; Dementia
• Interventions: Dietary Supplement: d-ribose

• Registration Number: NCT02260141
• Lead Sponsor: Practitioners Alliance Network

Brief Summary

To study the effectiveness of d-ribose in treating Alzheimer's and Dementia

Detailed Description

Clinical experience and the pathophysiology of Alzheimer's, including neuronal insulin resistance, suggests that ribose improves clinical outcomes. This study will add ribose 5 gm 3 X day for 8 weeks to monitor outcomes in a pilot study.

Study Timeline

• Study Start: 2014-09
• Study First Submitted: 2014-10-05
• Study First Submitted QC: 2014-10-08
• Study First Posted: 2014-10-09
• Status Verified: 2017-10
• Primary Completion: 2017-10
• Study Completion: 2017-10
• Last Update Submitted: 2020-05-06
• Last Update Posted: 2020-05-08

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 3

Inclusion Criteria

• A diagnosis of Alzheimer's and/or dementia with a Mini Mental Status Exam ( MMSE) score over 12 or being ambulatory and able to travel outside the home with assistance.
• Must have a caregiver living with them.

Exclusion Criteria

• Overt and severe causes of secondary dementia such as metastatic brain cancers, or severe overt infectious encephalopathies or severe autoimmune illness.
• Also, severe life threatening illnesses which would make them unlikely to be alive after 6-12 months.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Treatment with d-ribose	d-ribose	Treatment with ribose 5 gm TID

Primary Outcome Measures

Name	Time	Method
ADAS-ADL	2 months

Trial Locations

Locations (1)

PAN; 🇺🇸 Kailua, Hawaii, United States