TCTR20190709005已完成未知
Effect of narrowband ultraviolet B therapy on serum levels of CD26/dipeptidyl-peptidase IV and truncated form of substanceP in plaque-type psoriasis
The National Research Council of Thailand0 个研究点目标入组 13 人开始时间: 2019年7月9日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 13
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 80 Years（—）
- 性别
- All
入选标准
- •Inclusion criteria
- •â€¢Patient aged ≥ 18 years old.
- •â€¢Moderate to severe plaque-type psoriasis (Psoriasis Area and Severity Index; PASI >10) patient with pruritus.
排除标准
- •Exclusion criteria
- •â€¢Patients’ refusal to give a consent
- •â€¢Patient taking other treatment for the disease; topical therapies within 2 weeks, systemic therapies and phototherapy within 4 weeks prior the study period.
- •â€¢Patient with contraindication of narrowband UVB (e.g. xeroderma pigmentosum, other inherited disorder associated with UV-induced carcinogenesis, photodermatosis, history of skin cancer)
- •â€¢Patient with known history of photosensitivity
- •â€¢Presence of psoriasis arthritis
- •â€¢Patient with CD26 and DPPIV associated diseases -T-cell leukemia/lymphoma, as Mycosis fungoides (MF) and Sezary syndrome (SS), Non-Hodgkin's lymphoma, T-cell large granular lymphocyte leukemia, Systemic lupus erythematosus, rheumatoid arthritis, Diabetes mellitus, cancer, chronic diseases, HIV infection , Allergic disease , Atopic dermatitis
- •â€¢ Patient with substance P associated diseases and drugs
- •oChronic urticarial, Prurigo nodularis, Major depressive disorder, anxiety, Uremia, Diabetic mellitus, Chronic pancreatitis, Coronary artery disease, Ulcerative colitis and Crohn's disease, Behçet's disease, Inflammatory bowel disease, Sickle cell crisis, Rheumatological diseases, Infectious diseases (such as AIDS and respiratory syncytial virus), Cancer, Autoimmune myelofibrosis, Liver diseases and Cirrhosis
- •oNicergoline, Chemotherapy, Hormone therapy, Etanercept, Anti-histamine, Tropisetron
- •â€¢presence of autoimmune disease or immunocompromised conditions
- •â€¢unreliable and poor compliance patients
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