Impact of light therapy on bone strength and blood vitamin D levels in vitiligo patients
- Conditions
- Health Condition 1: L80- Vitiligo
- Registration Number
- CTRI/2023/03/050766
- Lead Sponsor
- Keshavamurthy Vinay
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1.Patients of non-segmental vitiligo involving 10-50% of body surface area
2.Age 12-60 years
3.Unstable disease, defined as occurrence of new lesion(s), progression of existing lesion(s) or Koebnerization
4.Should have received corticosteroids in any dose for >3 months
1.Patients of segmental vitiligo and universal vitiligo
2.Contraindication to use of NBUVB phototherapy including xeroderma pigmentosa, systemic lupus erythematosus and other photo-induced or photo-aggravated dermatoses
3.Intake of phototoxic drugs
4.History of skin malignancy, premalignant skin lesions and dysplastic naevi
5.Claustrophobia
6.Hepatic and renal dysfunction
7.Immunosuppression
8.Associated connective tissue diseases including but not limited to systemic lupus erythematosus, rheumatoid arthritis
9.Pregnancy and lactation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Measurement of bone mineral density using dual-energy X-ray absorptiometry (DEXA) at baseline and after 24 weeks. <br/ ><br>2. Measurement of serum vitamin D levels at baseline and after 24 weeksTimepoint: Baseline <br/ ><br>24 weeks
- Secondary Outcome Measures
Name Time Method oneTimepoint: None