COVID-19 and Acute Invasive Fungal Rhinosinusitis
Completed
- Conditions
- Covid19
- Interventions
- Diagnostic Test: Fungal rhinosinusitis
- Registration Number
- NCT04809480
- Lead Sponsor
- Al-Azhar University
- Brief Summary
Data for acute invasive rhinosinusitis was obtained from the Otorhinolaryngology departments at our tertiary hospital at the period from January 2017 to December 2020. Then the risk factors of comorbid diseases and fungal types between post-Covid-19 and non-Covid-19 groups regarding the incidence of invasive rhinosinusitis are compared.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 56
Inclusion Criteria
- Patients of any age and sex. invasive rhinosinusoitis diagnosis based on clinical , endoscopic diagnosis
- Positive findings for acute sinusitis on sinus computed tomography (CT) scan in addition to fungal determination by histopathological examination of specimen of affected tissues for detection of the type of fungi.
- Positive PCR was confirmed from the patient's files at the isolation hospitals for COVID 19 group.
Exclusion Criteria
- Patients who completed management outside our hospital
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Non-COVID19 patients Fungal rhinosinusitis All acute invasive fungal rhinosinusitis patients managed in our hospital from January 2017 up to February 2020 COVID19 patients Fungal rhinosinusitis All acute invasive fungal rhinosinusitis patients managed in our hospital from February 2020 up to December 2020 with positive COVID19 PCR test
- Primary Outcome Measures
Name Time Method Fungus detection 2 weeks Culture and microscopic examination by the light microscope to examine the different types of the fungi using hematoxylin \& eosin stain and Periodic acid-Schiff stain which is positive in fungi
- Secondary Outcome Measures
Name Time Method