NCT07514403尚未招募不适用
Assessment of the Biological Response of the Corticision During Intrusion of Lower Incisors A Prospective Clinical Study
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 16
- 主要终点
- Gingival crevicular fluid (GCF) prostaglandin E2 (PGE2) levels measured by enzyme-linked immunosorbent assay (ELISA) (pg/mL)
研究概览
简要总结
biological assesment during intrusion of lower incisors
详细描述
Assessment of the biological response of the corticision during intrusion of lower incisors A prospective clinical study
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 14 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients requiring extraction-based orthodontic treatment
- •Presence of deep overbite requiring lower incisor intrusion
- •Age range: 18-30 years
- •Good general health
- •Good oral hygiene
排除标准
- •Systemic diseases affecting bone metabolism
- •Previous orthodontic treatment
- •Periodontal disease
- •Pregnancy or lactation
研究组 & 干预措施
controlled
No Intervention
without corticision
active group
Active Comparator
corticision group
干预措施: Corticision (Other)
结局指标
主要结局
Gingival crevicular fluid (GCF) prostaglandin E2 (PGE2) levels measured by enzyme-linked immunosorbent assay (ELISA) (pg/mL)
时间窗: 12 weeks
GCF samples will be collected from lower incisors using microcapillary tubes at baseline and during follow-up visits. Prostaglandin E2 levels will be quantified using ELISA kits and expressed in pg/mL to assess the biological response to corticision-assisted intrusion.
次要结局
- Amount of lower incisor intrusion (mm) and external apical root resorption (mm) assessed using cone beam computed tomography (CBCT)(12 weeks)
- Amount of lower incisor intrusion measured in millimeters (mm) using cone beam computed tomography (CBCT)(12 weeks)
- External apical root resorption measured in millimeters (mm) using cone beam computed tomography (CBCT)(Time Frame: 12 weeks)
研究者
Alaa Eldin Elshahat Shafay Ali
postgraduate researcher
Al-Azhar University
相似试验
尚未招募
不适用
An observational trial to study the changes in the cortical bone thickness in edentulous areas within 1 year, 1 to 3 years and more than 3 years after extraction of teeth.CTRI/2025/04/085109Hazaribag College Of Dental Sciences and Hospital30
尚未招募
Phase 3 4
Comparison of amount of two teeth space closure techniquesCTRI/2024/07/070111Datta Meghe Institute of Higher Education and Research20
已完成
不适用
Salivary Cortisol Levels in Children With Molar Incisor HypomineralizationNCT07389148Lokman Hekim University91
尚未招募
4 期
Effect of surrounding Periodontal Hard and Soft Tissue Thickness on Dental Implant StabilityCTRI/2024/06/069392SGT Dental College Hospital and Research Institute SGT University Gurugram Haryana20
尚未招募
Phase 3 4
Study of the underlying changes in bone when tooth movement is brought about by orthodontic treatmentCTRI/2024/09/074517Pooja Lakshmanan6